Ouch. I'm usually always running Calendar, Mail, Safari, Notes, Skype, and Firefox.
Trying to figure out the keyboard command to open Computer in Finder. Shows some sort of Up Arrow + Command + C.
Command + R/W/T/Q says me a ton of time though. =D
I find it equally neat they swapped the F8 with the function keys. My old laptop used F8 keys as default and using the Alt function required holding fn, this is the opposite, which is nice.
You could turn the Fn functions on laptops on the BIOS. I always did that.
Also, Command + N opens a new tab on the Finder.